{"id":12076,"date":"2022-10-22T08:43:22","date_gmt":"2022-10-22T08:43:22","guid":{"rendered":"https:\/\/www.ttci-th.org\/?p=12076"},"modified":"2023-06-24T12:07:13","modified_gmt":"2023-06-24T12:07:13","slug":"researchers-develop-efficient-hybridoma-generation-strategy-for-promising-anti-pd-1-molecules-in-cancer-immunotherapy","status":"publish","type":"post","link":"https:\/\/www.ttci-th.org\/th\/researchers-develop-efficient-hybridoma-generation-strategy-for-promising-anti-pd-1-molecules-in-cancer-immunotherapy\/","title":{"rendered":"\u0e19\u0e31\u0e01\u0e27\u0e34\u0e08\u0e31\u0e22\u0e1e\u0e31\u0e12\u0e19\u0e32\u0e01\u0e25\u0e22\u0e38\u0e17\u0e18\u0e4c\u0e01\u0e32\u0e23\u0e2a\u0e23\u0e49\u0e32\u0e07\u0e25\u0e39\u0e01\u0e1c\u0e2a\u0e21\u0e2d\u0e22\u0e48\u0e32\u0e07\u0e21\u0e35\u0e1b\u0e23\u0e30\u0e2a\u0e34\u0e17\u0e18\u0e34\u0e20\u0e32\u0e1e\u0e2a\u0e33\u0e2b\u0e23\u0e31\u0e1a\u0e42\u0e21\u0e40\u0e25\u0e01\u0e38\u0e25\u0e15\u0e48\u0e2d\u0e15\u0e49\u0e32\u0e19 PD-1 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\u0e41\u0e25\u0e30\u0e01\u0e32\u0e23\u0e04\u0e31\u0e14\u0e40\u0e25\u0e37\u0e2d\u0e01\u0e44\u0e2e\u0e1a\u0e23\u0e34\u0e42\u0e14\u0e21\u0e32\u0e17\u0e35\u0e48\u0e21\u0e35\u0e1b\u0e23\u0e30\u0e2a\u0e34\u0e17\u0e18\u0e34\u0e20\u0e32\u0e1e \u0e0b\u0e36\u0e48\u0e07\u0e43\u0e19\u0e17\u0e49\u0e32\u0e22\u0e17\u0e35\u0e48\u0e2a\u0e38\u0e14\u0e43\u0e2b\u0e49\u0e15\u0e49\u0e19\u0e41\u0e1a\u0e1a\u0e15\u0e31\u0e27\u0e40\u0e25\u0e37\u0e2d\u0e01\u0e15\u0e49\u0e32\u0e19 PD-1 \u0e44\u0e04\u0e40\u0e21\u0e2d\u0e23\u0e34\u0e01\u0e2b\u0e49\u0e32\u0e15\u0e31\u0e27\u0e17\u0e35\u0e48\u0e21\u0e35\u0e28\u0e31\u0e01\u0e22\u0e20\u0e32\u0e1e \u0e15\u0e49\u0e19\u0e41\u0e1a\u0e1a xCUSB0103 \u0e44\u0e04\u0e40\u0e21\u0e2d\u0e23\u0e34\u0e01\u0e25\u0e35\u0e14\u0e41\u0e2a\u0e14\u0e07\u0e2a\u0e31\u0e21\u0e1e\u0e23\u0e23\u0e04\u0e20\u0e32\u0e1e\u0e43\u0e19\u0e01\u0e32\u0e23\u0e08\u0e31\u0e1a\u0e2a\u0e39\u0e07, \u0e01\u0e32\u0e23\u0e2d\u0e2d\u0e01\u0e24\u0e17\u0e18\u0e34\u0e4c\u0e43\u0e19\u0e01\u0e32\u0e23\u0e02\u0e31\u0e14\u0e02\u0e27\u0e32\u0e07\u0e01\u0e32\u0e23\u0e08\u0e31\u0e1a PD-1\/PD-L1 \u0e41\u0e25\u0e30\u0e04\u0e27\u0e32\u0e21\u0e2a\u0e32\u0e21\u0e32\u0e23\u0e16\u0e43\u0e19\u0e01\u0e32\u0e23\u0e01\u0e23\u0e30\u0e15\u0e38\u0e49\u0e19\u0e17\u0e35\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e43\u0e19\u0e2b\u0e25\u0e2d\u0e14\u0e17\u0e14\u0e25\u0e2d\u0e07, \u0e40\u0e1b\u0e23\u0e35\u0e22\u0e1a\u0e44\u0e14\u0e49\u0e01\u0e31\u0e1a OPDIVO, \u0e41\u0e2d\u0e19\u0e15\u0e34-PD-1 \u0e41\u0e2d\u0e19\u0e15\u0e34\u0e1a\u0e2d\u0e14\u0e35\u0e17\u0e35\u0e48\u0e21\u0e35\u0e08\u0e33\u0e2b\u0e19\u0e48\u0e32\u0e22\u0e43\u0e19\u0e17\u0e49\u0e2d\u0e07\u0e15\u0e25\u0e32\u0e14 \u0e1c\u0e25\u0e25\u0e31\u0e1e\u0e18\u0e4c\u0e40\u0e2b\u0e25\u0e48\u0e32\u0e19\u0e35\u0e49\u0e0a\u0e35\u0e49\u0e43\u0e2b\u0e49\u0e40\u0e2b\u0e47\u0e19\u0e27\u0e48\u0e32\u0e15\u0e49\u0e19\u0e41\u0e1a\u0e1a\u0e15\u0e30\u0e01\u0e31\u0e48\u0e27\u0e2d\u0e32\u0e08\u0e1e\u0e31\u0e12\u0e19\u0e32\u0e40\u0e1b\u0e47\u0e19 ICI \u0e43\u0e19\u0e23\u0e39\u0e1b\u0e41\u0e1a\u0e1a\u0e15\u0e48\u0e32\u0e07\u0e46 \u0e2a\u0e33\u0e2b\u0e23\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e1a\u0e33\u0e1a\u0e31\u0e14\u0e14\u0e49\u0e27\u0e22\u0e20\u0e39\u0e21\u0e34\u0e04\u0e38\u0e49\u0e21\u0e01\u0e31\u0e19\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07 \u0e01\u0e32\u0e23\u0e1e\u0e31\u0e12\u0e19\u0e32\u0e2d\u0e22\u0e48\u0e32\u0e07\u0e15\u0e48\u0e2d\u0e40\u0e19\u0e37\u0e48\u0e2d\u0e07\u0e02\u0e2d\u0e07\u0e42\u0e21\u0e40\u0e25\u0e01\u0e38\u0e25\u0e15\u0e48\u0e2d\u0e15\u0e49\u0e32\u0e19 PD-1 \u0e40\u0e1b\u0e47\u0e19\u0e2a\u0e34\u0e48\u0e07\u0e08\u0e33\u0e40\u0e1b\u0e47\u0e19\u0e2a\u0e33\u0e2b\u0e23\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e1a\u0e33\u0e1a\u0e31\u0e14\u0e14\u0e49\u0e27\u0e22\u0e20\u0e39\u0e21\u0e34\u0e04\u0e38\u0e49\u0e21\u0e01\u0e31\u0e19\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e22\u0e38\u0e04\u0e2b\u0e19\u0e49\u0e32 \u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e40\u0e1e\u0e34\u0e48\u0e21\u0e1b\u0e23\u0e30\u0e2a\u0e34\u0e17\u0e18\u0e34\u0e20\u0e32\u0e1e\u0e17\u0e32\u0e07\u0e04\u0e25\u0e34\u0e19\u0e34\u0e01\u0e2a\u0e39\u0e07\u0e2a\u0e38\u0e14\u0e41\u0e25\u0e30\u0e2b\u0e25\u0e35\u0e01\u0e40\u0e25\u0e35\u0e48\u0e22\u0e07\u0e04\u0e27\u0e32\u0e21\u0e02\u0e31\u0e14\u0e41\u0e22\u0e49\u0e07\u0e43\u0e19\u0e17\u0e23\u0e31\u0e1e\u0e22\u0e4c\u0e2a\u0e34\u0e19\u0e17\u0e32\u0e07\u0e1b\u0e31\u0e0d\u0e0d\u0e32<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-cb58e40 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no\" data-id=\"cb58e40\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-22372e9\" data-id=\"22372e9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d30471e elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"d30471e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.16.0 - 14-09-2023 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-default\">\u0e40\u0e07\u0e34\u0e19\u0e17\u0e38\u0e19<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c669d49 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"c669d49\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - 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elementor-widget elementor-widget-text-editor\" data-id=\"86b218e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>\u0e01\u0e32\u0e23\u0e28\u0e36\u0e01\u0e29\u0e32\u0e19\u0e35\u0e49\u0e08\u0e31\u0e14\u0e17\u0e33\u0e42\u0e14\u0e22\u0e42\u0e04\u0e23\u0e07\u0e01\u0e32\u0e23\u0e08\u0e38\u0e2c\u0e32\u0e2f \u0e27\u0e34\u0e0a\u0e32\u0e01\u0e32\u0e23 \u0e01\u0e49\u0e32\u0e27\u0e2a\u0e39\u0e48\u0e28\u0e15\u0e27\u0e23\u0e23\u0e29\u0e17\u0e35\u0e48\u0e2a\u0e2d\u0e07 (CUAASC) \u0e15.\u0e1c\u0e31\u0e01\u0e04\u0e33 \u0e44\u0e14\u0e49\u0e23\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e2a\u0e19\u0e31\u0e1a\u0e2a\u0e19\u0e38\u0e19\u0e08\u0e32\u0e01\u0e01\u0e2d\u0e07\u0e17\u0e38\u0e19 100 \u0e1b\u0e35 \u0e08\u0e38\u0e2c\u0e32\u0e25\u0e07\u0e01\u0e23\u0e13\u0e4c\u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e17\u0e38\u0e19\u0e14\u0e38\u0e29\u0e0e\u0e35\u0e1a\u0e31\u0e13\u0e11\u0e34\u0e15 \u0e41\u0e25\u0e30\u0e01\u0e2d\u0e07\u0e17\u0e38\u0e19 90 \u0e1b\u0e35 \u0e08\u0e38\u0e2c\u0e32\u0e25\u0e07\u0e01\u0e23\u0e13\u0e4c\u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22 (\u0e01\u0e2d\u0e07\u0e17\u0e38\u0e19\u0e23\u0e31\u0e0a\u0e14\u0e32\u0e20\u0e34\u0e40\u0e29\u0e01\u0e2a\u0e21\u0e42\u0e20\u0e0a)<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4c83c4f elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no\" data-id=\"4c83c4f\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b7b252a\" data-id=\"b7b252a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0af7efe elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"0af7efe\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\n\u0e01\u0e23\u0e30\u0e14\u0e32\u0e29\u0e15\u0e49\u0e19\u0e09\u0e1a\u0e31\u0e1a<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-75c62f9 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"75c62f9\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a66d4fb elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"a66d4fb\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>\u0e0a\u0e37\u0e48\u0e2d\u0e1a\u0e17\u0e04\u0e27\u0e32\u0e21\u0e15\u0e49\u0e19\u0e09\u0e1a\u0e31\u0e1a: <\/strong>\u0e01\u0e32\u0e23\u0e2a\u0e23\u0e49\u0e32\u0e07\u0e44\u0e2e\u0e1a\u0e23\u0e34\u0e42\u0e14\u0e21\u0e32\u0e41\u0e25\u0e30\u0e01\u0e25\u0e22\u0e38\u0e17\u0e18\u0e4c\u0e01\u0e32\u0e23\u0e04\u0e31\u0e14\u0e01\u0e23\u0e2d\u0e07\u0e17\u0e35\u0e48\u0e21\u0e35\u0e1b\u0e23\u0e30\u0e2a\u0e34\u0e17\u0e18\u0e34\u0e20\u0e32\u0e1e\u0e2a\u0e39\u0e07\u0e2a\u0e33\u0e2b\u0e23\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e1e\u0e31\u0e12\u0e19\u0e32\u0e41\u0e2d\u0e19\u0e15\u0e34-PD-1 \u0e42\u0e21\u0e42\u0e19\u0e42\u0e04\u0e25\u0e19\u0e2d\u0e25\u0e41\u0e2d\u0e19\u0e15\u0e34\u0e1a\u0e2d\u0e14\u0e35<br \/><strong>\u0e27\u0e32\u0e23\u0e2a\u0e32\u0e23:<\/strong> \u0e15\u0e31\u0e27\u0e41\u0e17\u0e19\u0e27\u0e34\u0e17\u0e22\u0e4c<br \/><strong>\u0e14\u0e2d\u0e22:<\/strong> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36273231\/\">10.1038\/s41598-022-20560-6<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5c5d082 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no\" data-id=\"5c5d082\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d7e3d8d\" data-id=\"d7e3d8d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8a45000 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"8a45000\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u0e08\u0e14\u0e2b\u0e21\u0e32\u0e22\u0e42\u0e15\u0e49\u0e15\u0e2d\u0e1a<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c066f60 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"c066f60\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8df055a elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"8df055a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>\u0e44\u0e15\u0e23\u0e23\u0e31\u0e01\u0e29\u0e4c \u0e1e\u0e34\u0e2a\u0e34\u0e29\u0e10\u0e4c\u0e01\u0e38\u0e25<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2c1867f elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no\" data-id=\"2c1867f\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a2eab42\" data-id=\"a2eab42\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-86313e1 elementor-widget__width-initial elementor-widget elementor-widget-jkit_social_share\" data-id=\"86313e1\" data-element_type=\"widget\" data-widget_type=\"jkit_social_share.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div  class=\"jeg-elementor-kit jkit-social-share jeg_module___6abf1e1fa34a4\" ><ul class=\"social-share-list\"><li class=\"elementor-repeater-item-14d1b21\" data-social=\"facebook\">\n\t\t\t\t<a class=\"facebook social-icon\"><span class=\"icon-position-before\"><i aria-hidden=\"true\" class=\"fab fa-facebook-f\"><\/i>\u0e40\u0e1f\u0e2a\u0e1a\u0e38\u0e4a\u0e04<\/span><\/a>\n\t\t\t<\/li><li class=\"elementor-repeater-item-ee9a855\" data-social=\"twitter\">\n\t\t\t\t<a class=\"twitter social-icon\"><span class=\"icon-position-before\"><i aria-hidden=\"true\" class=\"fab fa-twitter\"><\/i>\u0e17\u0e27\u0e34\u0e15\u0e40\u0e15\u0e2d\u0e23\u0e4c<\/span><\/a>\n\t\t\t<\/li><li class=\"elementor-repeater-item-4a6d796\" data-social=\"line\">\n\t\t\t\t<a class=\"line social-icon\"><span class=\"icon-position-before\"><i aria-hidden=\"true\" class=\"fab fa-line\"><\/i>\u0e40\u0e2a\u0e49\u0e19<\/span><\/a>\n\t\t\t<\/li><\/ul><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>A team of researchers from Chulalongkorn University has developed a highly efficient hybridoma generation and screening strategy to generate high-potency chimeric anti-PD-1 molecules, a protein that plays a significant role in suppressing antitumor immune responses. The lead chimeric prototypes exhibited overall in vitro performance comparable to commercially available anti-PD-1 antibodies and could be qualified as&#8230;<\/p>","protected":false},"author":2,"featured_media":15065,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[65],"tags":[72],"class_list":["post-12076","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-news-chulalongkorn-university","tag-tag-news-cu"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.2 - aioseo.com -->\n\t<meta name=\"description\" content=\"A team of researchers from Chulalongkorn University has developed a highly efficient hybridoma generation and screening strategy to generate high-potency chimeric anti-PD-1 molecules, a protein that plays a significant role in suppressing antitumor immune responses. The lead chimeric prototypes exhibited overall in vitro performance comparable to commercially available anti-PD-1 antibodies and could be qualified as\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"admin\"\/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.ttci-th.org\/th\/researchers-develop-efficient-hybridoma-generation-strategy-for-promising-anti-pd-1-molecules-in-cancer-immunotherapy\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 5.0.2\" \/>\n\t\t<meta property=\"og:locale\" content=\"th_TH\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Thailand Hub of Talents in Cancer Immunotherapy (TTCI Thailand) - TTCI-TH\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"Researchers Develop Efficient Hybridoma Generation Strategy for Promising Anti-PD-1 Molecules in Cancer Immunotherapy\" \/>\n\t\t<meta property=\"og:description\" content=\"A team of researchers from Chulalongkorn University has developed a highly efficient hybridoma generation and screening strategy to generate high-potency chimeric anti-PD-1 molecules, a protein that plays a significant role in suppressing antitumor immune responses. 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17:52:00","updated":"2026-09-03 06:42:03","focus_keyword":"Anti-PD-1","additional_keywords":null,"truseo_locale":null,"ai":null,"breadcrumb_settings":null,"seo_analyzer_scan_date":null},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.ttci-th.org\/th\/\" title=\"Home\">Home<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">\u00bb<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.ttci-th.org\/th\/category\/research-news\/\" title=\"Research News\">Research News<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">\u00bb<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/www.ttci-th.org\/th\/category\/research-news\/research-news-chulalongkorn-university\/\" title=\"Chulalongkorn University\">Chulalongkorn University<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">\u00bb<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\tResearchers Develop 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