{"id":14468,"date":"2022-01-01T10:15:06","date_gmt":"2022-01-01T10:15:06","guid":{"rendered":"https:\/\/www.ttci-th.org\/?p=14468"},"modified":"2023-06-24T16:00:01","modified_gmt":"2023-06-24T16:00:01","slug":"groundbreaking-research-shows-promise-in-the-development-of-improved-car-t-cell-therapy-for-b-cell-malignancies","status":"publish","type":"post","link":"https:\/\/www.ttci-th.org\/th\/groundbreaking-research-shows-promise-in-the-development-of-improved-car-t-cell-therapy-for-b-cell-malignancies\/","title":{"rendered":"\u0e01\u0e32\u0e23\u0e27\u0e34\u0e08\u0e31\u0e22\u0e17\u0e35\u0e48\u0e01\u0e49\u0e32\u0e27\u0e25\u0e49\u0e33\u0e41\u0e2a\u0e14\u0e07\u0e43\u0e2b\u0e49\u0e40\u0e2b\u0e47\u0e19\u0e16\u0e36\u0e07\u0e04\u0e33\u0e21\u0e31\u0e48\u0e19\u0e2a\u0e31\u0e0d\u0e0d\u0e32\u0e43\u0e19\u0e01\u0e32\u0e23\u0e1e\u0e31\u0e12\u0e19\u0e32\u0e01\u0e32\u0e23\u0e1a\u0e33\u0e1a\u0e31\u0e14\u0e14\u0e49\u0e27\u0e22\u0e40\u0e0b\u0e25\u0e25\u0e4c T-cell \u0e17\u0e35\u0e48\u0e44\u0e14\u0e49\u0e23\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e1b\u0e23\u0e31\u0e1a\u0e1b\u0e23\u0e38\u0e07\u0e2a\u0e33\u0e2b\u0e23\u0e31\u0e1a\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e40\u0e0b\u0e25\u0e25\u0e4c B"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"14468\" class=\"elementor elementor-14468\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9e9621b elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no\" data-id=\"9e9621b\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-218319c\" data-id=\"218319c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-f6d8091\" data-id=\"f6d8091\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-80dd4c1\" data-id=\"80dd4c1\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-4be962c\" data-id=\"4be962c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-21e348c elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"21e348c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.16.0 - 14-09-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<div>\u0e20\u0e32\u0e1e\u0e16\u0e48\u0e32\u0e22\u0e42\u0e14\u0e22 RF._.studio\/pexels<\/div><div id=\"2BA85E87_4BC3_472E_41F0_2FF79C2C6F72\">\u00a0<\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b9af823 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no\" data-id=\"b9af823\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2db16c3\" data-id=\"2db16c3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e57f26e elementor-widget elementor-widget-text-editor\" data-id=\"e57f26e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>\u0e43\u0e19\u0e04\u0e27\u0e32\u0e21\u0e01\u0e49\u0e32\u0e27\u0e2b\u0e19\u0e49\u0e32\u0e04\u0e23\u0e31\u0e49\u0e07\u0e2a\u0e33\u0e04\u0e31\u0e0d\u0e2a\u0e33\u0e2b\u0e23\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e23\u0e31\u0e01\u0e29\u0e32\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e1a\u0e35\u0e40\u0e0b\u0e25\u0e25\u0e4c \u0e19\u0e31\u0e01\u0e27\u0e34\u0e08\u0e31\u0e22\u0e44\u0e14\u0e49\u0e1e\u0e31\u0e12\u0e19\u0e32\u0e17\u0e35\u0e40\u0e0b\u0e25\u0e25\u0e4c \u0e44\u0e04\u0e40\u0e21\u0e2d\u0e23\u0e34\u0e01 \u0e41\u0e2d\u0e19\u0e15\u0e34\u0e40\u0e08\u0e19 \u0e23\u0e35\u0e40\u0e0b\u0e1e\u0e40\u0e15\u0e2d\u0e23\u0e4c (CAR) \u0e23\u0e38\u0e48\u0e19\u0e43\u0e2b\u0e21\u0e48\u0e17\u0e35\u0e48\u0e21\u0e35\u0e2a\u0e48\u0e27\u0e19\u0e1b\u0e23\u0e30\u0e01\u0e2d\u0e1a\u0e17\u0e35\u0e48\u0e44\u0e14\u0e49\u0e21\u0e32\u0e08\u0e32\u0e01\u0e21\u0e19\u0e38\u0e29\u0e22\u0e4c\u0e2d\u0e22\u0e48\u0e32\u0e07\u0e2a\u0e21\u0e1a\u0e39\u0e23\u0e13\u0e4c \u0e0b\u0e36\u0e48\u0e07\u0e19\u0e33\u0e40\u0e2a\u0e19\u0e2d\u0e01\u0e32\u0e23\u0e1b\u0e23\u0e31\u0e1a\u0e1b\u0e23\u0e38\u0e07\u0e17\u0e35\u0e48\u0e21\u0e35\u0e28\u0e31\u0e01\u0e22\u0e20\u0e32\u0e1e\u0e40\u0e2b\u0e19\u0e37\u0e2d\u0e01\u0e32\u0e23\u0e23\u0e31\u0e01\u0e29\u0e32\u0e43\u0e19\u0e1b\u0e31\u0e08\u0e08\u0e38\u0e1a\u0e31\u0e19 \u0e01\u0e32\u0e23\u0e1a\u0e33\u0e1a\u0e31\u0e14\u0e14\u0e49\u0e27\u0e22\u0e40\u0e0b\u0e25\u0e25\u0e4c T-CAR \u0e44\u0e14\u0e49\u0e41\u0e2a\u0e14\u0e07\u0e43\u0e2b\u0e49\u0e40\u0e2b\u0e47\u0e19\u0e1b\u0e23\u0e30\u0e2a\u0e34\u0e17\u0e18\u0e34\u0e20\u0e32\u0e1e\u0e43\u0e19\u0e01\u0e32\u0e23\u0e23\u0e31\u0e01\u0e29\u0e32\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e40\u0e0b\u0e25\u0e25\u0e4c B \u0e41\u0e15\u0e48\u0e01\u0e32\u0e23\u0e04\u0e07\u0e2d\u0e22\u0e39\u0e48\u0e02\u0e2d\u0e07\u0e40\u0e0b\u0e25\u0e25\u0e4c CAR T \u0e1a\u0e32\u0e07\u0e0a\u0e19\u0e34\u0e14\u0e41\u0e25\u0e30\u0e01\u0e32\u0e23\u0e15\u0e2d\u0e1a\u0e2a\u0e19\u0e2d\u0e07\u0e17\u0e32\u0e07\u0e20\u0e39\u0e21\u0e34\u0e04\u0e38\u0e49\u0e21\u0e01\u0e31\u0e19\u0e17\u0e35\u0e48\u0e40\u0e1b\u0e47\u0e19\u0e1c\u0e25\u0e17\u0e33\u0e43\u0e2b\u0e49\u0e40\u0e01\u0e34\u0e14\u0e04\u0e27\u0e32\u0e21\u0e17\u0e49\u0e32\u0e17\u0e32\u0e22\u0e17\u0e35\u0e48\u0e2d\u0e32\u0e08\u0e19\u0e33\u0e44\u0e1b\u0e2a\u0e39\u0e48\u0e01\u0e32\u0e23\u0e01\u0e33\u0e40\u0e23\u0e34\u0e1a\u0e02\u0e2d\u0e07\u0e40\u0e19\u0e37\u0e49\u0e2d\u0e07\u0e2d\u0e01 \u0e40\u0e0b\u0e25\u0e25\u0e4c CAR T \u0e41\u0e1a\u0e1a\u0e43\u0e2b\u0e21\u0e48\u0e17\u0e35\u0e48\u0e21\u0e35\u0e0a\u0e37\u0e48\u0e2d\u0e27\u0e48\u0e32 Hu1E7-CAR4 T \u0e40\u0e0b\u0e25\u0e25\u0e4c \u0e21\u0e35\u0e08\u0e38\u0e14\u0e21\u0e38\u0e48\u0e07\u0e2b\u0e21\u0e32\u0e22\u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e08\u0e31\u0e14\u0e01\u0e32\u0e23\u0e01\u0e31\u0e1a\u0e02\u0e49\u0e2d\u0e08\u0e33\u0e01\u0e31\u0e14\u0e40\u0e2b\u0e25\u0e48\u0e32\u0e19\u0e35\u0e49\u0e42\u0e14\u0e22\u0e01\u0e32\u0e23\u0e23\u0e27\u0e21\u0e40\u0e2d\u0e32\u0e0a\u0e34\u0e49\u0e19\u0e2a\u0e48\u0e27\u0e19\u0e15\u0e31\u0e27\u0e41\u0e1b\u0e23\u0e2a\u0e32\u0e22\u0e42\u0e0b\u0e48\u0e40\u0e14\u0e35\u0e48\u0e22\u0e27\u0e02\u0e2d\u0e07\u0e21\u0e19\u0e38\u0e29\u0e22\u0e4c (scFv) \u0e17\u0e35\u0e48\u0e08\u0e33\u0e40\u0e1e\u0e32\u0e30\u0e40\u0e08\u0e32\u0e30\u0e08\u0e07\u0e01\u0e31\u0e1a\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e17\u0e35\u0e48\u0e21\u0e35 CD19 \u0e1a\u0e27\u0e01\u0e40\u0e02\u0e49\u0e32\u0e44\u0e27\u0e49\u0e14\u0e49\u0e27\u0e22\u0e01\u0e31\u0e19<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e1b683c elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no\" data-id=\"e1b683c\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-fc1e61f\" data-id=\"fc1e61f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e0f513f elementor-widget elementor-widget-text-editor\" data-id=\"e0f513f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>\u0e01\u0e32\u0e23\u0e27\u0e34\u0e08\u0e31\u0e22\u0e21\u0e38\u0e48\u0e07\u0e40\u0e19\u0e49\u0e19\u0e44\u0e1b\u0e17\u0e35\u0e48\u0e01\u0e32\u0e23\u0e40\u0e2d\u0e32\u0e0a\u0e19\u0e30\u0e01\u0e32\u0e23\u0e15\u0e2d\u0e1a\u0e2a\u0e19\u0e2d\u0e07\u0e17\u0e32\u0e07\u0e20\u0e39\u0e21\u0e34\u0e04\u0e38\u0e49\u0e21\u0e01\u0e31\u0e19\u0e17\u0e35\u0e48\u0e40\u0e01\u0e34\u0e14\u0e08\u0e32\u0e01\u0e40\u0e0b\u0e25\u0e25\u0e4c CAR T \u0e17\u0e35\u0e48\u0e44\u0e14\u0e49\u0e21\u0e32\u0e08\u0e32\u0e01 murine \u0e0b\u0e36\u0e48\u0e07\u0e2a\u0e32\u0e21\u0e32\u0e23\u0e16\u0e25\u0e14\u0e04\u0e27\u0e32\u0e21\u0e04\u0e07\u0e2d\u0e22\u0e39\u0e48\u0e41\u0e25\u0e30\u0e1b\u0e23\u0e30\u0e2a\u0e34\u0e17\u0e18\u0e34\u0e20\u0e32\u0e1e\u0e01\u0e32\u0e23\u0e23\u0e31\u0e01\u0e29\u0e32\u0e44\u0e14\u0e49 \u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e43\u0e2b\u0e49\u0e1a\u0e23\u0e23\u0e25\u0e38\u0e40\u0e1b\u0e49\u0e32\u0e2b\u0e21\u0e32\u0e22\u0e19\u0e35\u0e49 \u0e19\u0e31\u0e01\u0e27\u0e34\u0e08\u0e31\u0e22\u0e44\u0e14\u0e49\u0e41\u0e22\u0e01 scFv \u0e02\u0e2d\u0e07\u0e21\u0e19\u0e38\u0e29\u0e22\u0e4c\u0e0a\u0e37\u0e48\u0e2d Hu1E7 \u0e2d\u0e2d\u0e01\u0e08\u0e32\u0e01\u0e44\u0e25\u0e1a\u0e23\u0e32\u0e23\u0e35\u0e01\u0e32\u0e23\u0e41\u0e2a\u0e14\u0e07\u0e1c\u0e25\u0e02\u0e2d\u0e07 phage \u0e08\u0e32\u0e01\u0e19\u0e31\u0e49\u0e19 \u0e1e\u0e27\u0e01\u0e40\u0e02\u0e32\u0e2b\u0e25\u0e2d\u0e21\u0e23\u0e27\u0e21 Hu1E7 \u0e40\u0e02\u0e49\u0e32\u0e01\u0e31\u0e1a\u0e1a\u0e23\u0e34\u0e40\u0e27\u0e13\u0e1a\u0e32\u0e19\u0e1e\u0e31\u0e1a\u0e02\u0e2d\u0e07 CD8\u03b1, \u0e42\u0e14\u0e40\u0e21\u0e19\u0e17\u0e23\u0e32\u0e19\u0e2a\u0e4c\u0e40\u0e21\u0e21\u0e40\u0e1a\u0e23\u0e19\u0e02\u0e2d\u0e07 CD28, \u0e2a\u0e32\u0e21\u0e42\u0e14\u0e40\u0e21\u0e19\u0e15\u0e49\u0e19\u0e17\u0e38\u0e19\u0e01\u0e23\u0e30\u0e15\u0e38\u0e49\u0e19\u0e20\u0e32\u0e22\u0e43\u0e19\u0e40\u0e0b\u0e25\u0e25\u0e4c (CD28, 4-1BB \u0e41\u0e25\u0e30 CD27) \u0e41\u0e25\u0e30\u0e42\u0e14\u0e40\u0e21\u0e19\u0e01\u0e32\u0e23\u0e2a\u0e48\u0e07\u0e2a\u0e31\u0e0d\u0e0d\u0e32\u0e13 CD3\u03b6 \u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e2a\u0e23\u0e49\u0e32\u0e07\u0e40\u0e0b\u0e25\u0e25\u0e4c Hu1E7-CAR4 T<\/p><p>\u0e17\u0e35\u0e21\u0e27\u0e34\u0e08\u0e31\u0e22\u0e44\u0e14\u0e49\u0e40\u0e1b\u0e23\u0e35\u0e22\u0e1a\u0e40\u0e17\u0e35\u0e22\u0e1a\u0e24\u0e17\u0e18\u0e34\u0e4c\u0e15\u0e49\u0e32\u0e19\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e41\u0e25\u0e30\u0e01\u0e32\u0e23\u0e17\u0e33\u0e07\u0e32\u0e19\u0e02\u0e2d\u0e07 T \u0e40\u0e0b\u0e25\u0e25\u0e4c Hu1E7-CAR4 \u0e01\u0e31\u0e1a CAR T \u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e17\u0e35\u0e48\u0e44\u0e14\u0e49\u0e08\u0e32\u0e01 murine \u0e0b\u0e36\u0e48\u0e07\u0e23\u0e27\u0e21\u0e16\u0e36\u0e07 mFMC63-CAR2 T \u0e40\u0e0b\u0e25\u0e25\u0e4c (BB\u03b6) \u0e41\u0e25\u0e30 mFMC63-CAR3 T \u0e40\u0e0b\u0e25\u0e25\u0e4c (BB27\u03b6) \u0e43\u0e19\u0e01\u0e32\u0e23\u0e1b\u0e23\u0e30\u0e40\u0e21\u0e34\u0e19\u0e1e\u0e23\u0e35\u0e04\u0e25\u0e34\u0e19\u0e34\u0e01 \u0e17\u0e35\u0e40\u0e0b\u0e25\u0e25\u0e4c Hu1E7-CAR4 \u0e41\u0e2a\u0e14\u0e07\u0e24\u0e17\u0e18\u0e34\u0e4c\u0e15\u0e49\u0e32\u0e19\u0e40\u0e19\u0e37\u0e49\u0e2d\u0e07\u0e2d\u0e01\u0e17\u0e35\u0e48\u0e40\u0e2b\u0e19\u0e37\u0e2d\u0e01\u0e27\u0e48\u0e32\u0e01\u0e31\u0e1a\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e40\u0e1b\u0e49\u0e32\u0e2b\u0e21\u0e32\u0e22\u0e23\u0e32\u0e08\u0e34\u0e17\u0e35\u0e48\u0e21\u0e35 CD19 \u0e40\u0e1b\u0e47\u0e19\u0e1a\u0e27\u0e01 \u0e0b\u0e36\u0e48\u0e07\u0e04\u0e25\u0e49\u0e32\u0e22\u0e01\u0e31\u0e1a\u0e17\u0e35\u0e40\u0e0b\u0e25\u0e25\u0e4c mFMC63-CAR4 (28BB27\u03b6) \u0e17\u0e31\u0e49\u0e07 Hu1E7-CAR4 \u0e41\u0e25\u0e30 mFMC63-CAR4 \u0e17\u0e35\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e41\u0e2a\u0e14\u0e07\u0e04\u0e27\u0e32\u0e21\u0e40\u0e1b\u0e47\u0e19\u0e1e\u0e34\u0e29\u0e15\u0e48\u0e2d\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e41\u0e25\u0e30\u0e01\u0e32\u0e23\u0e40\u0e1e\u0e34\u0e48\u0e21\u0e08\u0e33\u0e19\u0e27\u0e19\u0e17\u0e35\u0e48\u0e40\u0e1b\u0e23\u0e35\u0e22\u0e1a\u0e40\u0e17\u0e35\u0e22\u0e1a\u0e01\u0e31\u0e19\u0e44\u0e14\u0e49<\/p><p>\u0e17\u0e35\u0e48\u0e19\u0e48\u0e32\u0e2a\u0e19\u0e43\u0e08\u0e04\u0e37\u0e2d \u0e19\u0e31\u0e01\u0e27\u0e34\u0e08\u0e31\u0e22\u0e2a\u0e31\u0e07\u0e40\u0e01\u0e15\u0e27\u0e48\u0e32 Hu1E7-CAR4 T \u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e2b\u0e25\u0e31\u0e48\u0e07\u0e44\u0e0b\u0e42\u0e15\u0e44\u0e04\u0e19\u0e4c\u0e43\u0e19\u0e23\u0e30\u0e14\u0e31\u0e1a\u0e17\u0e35\u0e48\u0e15\u0e48\u0e33\u0e01\u0e27\u0e48\u0e32 \u0e40\u0e0a\u0e48\u0e19 IFN-\u03b3 \u0e41\u0e25\u0e30 TNF-\u03b1 \u0e40\u0e21\u0e37\u0e48\u0e2d\u0e40\u0e1b\u0e23\u0e35\u0e22\u0e1a\u0e40\u0e17\u0e35\u0e22\u0e1a\u0e01\u0e31\u0e1a mFMC63-CAR4 T \u0e40\u0e0b\u0e25\u0e25\u0e4c \u0e2a\u0e34\u0e48\u0e07\u0e19\u0e35\u0e49\u0e2d\u0e32\u0e08\u0e21\u0e35\u0e2a\u0e32\u0e40\u0e2b\u0e15\u0e38\u0e21\u0e32\u0e08\u0e32\u0e01\u0e04\u0e27\u0e32\u0e21\u0e2a\u0e31\u0e21\u0e1e\u0e31\u0e19\u0e18\u0e4c\u0e43\u0e19\u0e01\u0e32\u0e23\u0e08\u0e31\u0e1a\u0e17\u0e35\u0e48\u0e15\u0e48\u0e33\u0e01\u0e27\u0e48\u0e32\u0e02\u0e2d\u0e07 Hu1E7-CAR4 \u0e17\u0e35\u0e40\u0e0b\u0e25\u0e25\u0e4c \u0e2d\u0e22\u0e48\u0e32\u0e07\u0e44\u0e23\u0e01\u0e47\u0e15\u0e32\u0e21 \u0e01\u0e32\u0e23\u0e04\u0e49\u0e19\u0e1e\u0e1a\u0e19\u0e35\u0e49\u0e41\u0e2a\u0e14\u0e07\u0e43\u0e2b\u0e49\u0e40\u0e2b\u0e47\u0e19\u0e16\u0e36\u0e07\u0e04\u0e27\u0e32\u0e21\u0e2a\u0e33\u0e40\u0e23\u0e47\u0e08\u0e43\u0e19\u0e01\u0e32\u0e23\u0e2a\u0e23\u0e49\u0e32\u0e07\u0e40\u0e0b\u0e25\u0e25\u0e4c CAR T \u0e0b\u0e36\u0e48\u0e07\u0e23\u0e27\u0e21\u0e40\u0e2d\u0e32 scFv \u0e17\u0e35\u0e48\u0e44\u0e14\u0e49\u0e21\u0e32\u0e08\u0e32\u0e01\u0e21\u0e19\u0e38\u0e29\u0e22\u0e4c\u0e2d\u0e22\u0e48\u0e32\u0e07\u0e2a\u0e21\u0e1a\u0e39\u0e23\u0e13\u0e4c\u0e0b\u0e36\u0e48\u0e07\u0e08\u0e33\u0e40\u0e1e\u0e32\u0e30\u0e15\u0e48\u0e2d\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e17\u0e35\u0e48\u0e21\u0e35 CD19 \u0e40\u0e1b\u0e47\u0e19\u0e1a\u0e27\u0e01<\/p><p>\u0e02\u0e31\u0e49\u0e19\u0e15\u0e2d\u0e19\u0e15\u0e48\u0e2d\u0e44\u0e1b\u0e2a\u0e33\u0e2b\u0e23\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e27\u0e34\u0e08\u0e31\u0e22\u0e19\u0e35\u0e49\u0e40\u0e01\u0e35\u0e48\u0e22\u0e27\u0e02\u0e49\u0e2d\u0e07\u0e01\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e28\u0e36\u0e01\u0e29\u0e32\u0e43\u0e19\u0e23\u0e48\u0e32\u0e07\u0e01\u0e32\u0e22 \u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e1b\u0e23\u0e30\u0e40\u0e21\u0e34\u0e19\u0e1b\u0e23\u0e30\u0e2a\u0e34\u0e17\u0e18\u0e34\u0e20\u0e32\u0e1e\u0e41\u0e25\u0e30\u0e04\u0e27\u0e32\u0e21\u0e1b\u0e25\u0e2d\u0e14\u0e20\u0e31\u0e22\u0e02\u0e2d\u0e07\u0e01\u0e32\u0e23\u0e15\u0e48\u0e2d\u0e15\u0e49\u0e32\u0e19\u0e40\u0e19\u0e37\u0e49\u0e2d\u0e07\u0e2d\u0e01\u0e41\u0e25\u0e30\u0e04\u0e27\u0e32\u0e21\u0e1b\u0e25\u0e2d\u0e14\u0e20\u0e31\u0e22\u0e02\u0e2d\u0e07\u0e17\u0e35\u0e40\u0e0b\u0e25\u0e25\u0e4c Hu1E7-CAR4 \u0e40\u0e21\u0e37\u0e48\u0e2d\u0e40\u0e1b\u0e23\u0e35\u0e22\u0e1a\u0e40\u0e17\u0e35\u0e22\u0e1a\u0e01\u0e31\u0e1a\u0e17\u0e35\u0e40\u0e0b\u0e25\u0e25\u0e4c mFMC63-CAR4<\/p><p>\u0e28.\u0e1e\u0e0d.\u0e44\u0e1c\u0e17 \u0e40\u0e22\u0e47\u0e19\u0e08\u0e34\u0e15\u0e42\u0e2a\u0e21\u0e19\u0e31\u0e2a \u0e1c\u0e39\u0e49\u0e40\u0e02\u0e35\u0e22\u0e19\u0e2d\u0e32\u0e27\u0e38\u0e42\u0e2a\u0e02\u0e2d\u0e07\u0e07\u0e32\u0e19\u0e27\u0e34\u0e08\u0e31\u0e22\u0e19\u0e35\u0e49 \u0e01\u0e25\u0e48\u0e32\u0e27\u0e27\u0e48\u0e32 \u201c\u0e07\u0e32\u0e19\u0e27\u0e34\u0e08\u0e31\u0e22\u0e02\u0e2d\u0e07\u0e40\u0e23\u0e32\u0e16\u0e37\u0e2d\u0e40\u0e1b\u0e47\u0e19\u0e01\u0e49\u0e32\u0e27\u0e2a\u0e33\u0e04\u0e31\u0e0d\u0e02\u0e2d\u0e07\u0e01\u0e32\u0e23\u0e1a\u0e33\u0e1a\u0e31\u0e14\u0e14\u0e49\u0e27\u0e22\u0e40\u0e0b\u0e25\u0e25\u0e4c CAR T-cell \u0e14\u0e49\u0e27\u0e22\u0e01\u0e32\u0e23\u0e1e\u0e31\u0e12\u0e19\u0e32 Hu1E7-CAR4 T \u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e14\u0e49\u0e27\u0e22\u0e2a\u0e48\u0e27\u0e19\u0e1b\u0e23\u0e30\u0e01\u0e2d\u0e1a\u0e17\u0e35\u0e48\u0e44\u0e14\u0e49\u0e21\u0e32\u0e08\u0e32\u0e01\u0e21\u0e19\u0e38\u0e29\u0e22\u0e4c\u0e2d\u0e22\u0e48\u0e32\u0e07\u0e2a\u0e21\u0e1a\u0e39\u0e23\u0e13\u0e4c \u0e40\u0e23\u0e32\u0e21\u0e35\u0e40\u0e1b\u0e49\u0e32\u0e2b\u0e21\u0e32\u0e22\u0e17\u0e35\u0e48\u0e08\u0e30\u0e08\u0e31\u0e14\u0e01\u0e32\u0e23\u0e01\u0e31\u0e1a\u0e04\u0e27\u0e32\u0e21\u0e17\u0e49\u0e32\u0e17\u0e32\u0e22\u0e17\u0e35\u0e48\u0e40\u0e01\u0e35\u0e48\u0e22\u0e27\u0e02\u0e49\u0e2d\u0e07\u0e01\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e15\u0e2d\u0e1a\u0e2a\u0e19\u0e2d\u0e07\u0e02\u0e2d\u0e07\u0e23\u0e30\u0e1a\u0e1a\u0e20\u0e39\u0e21\u0e34\u0e04\u0e38\u0e49\u0e21\u0e01\u0e31\u0e19 \u0e41\u0e25\u0e30\u0e1b\u0e23\u0e31\u0e1a\u0e1b\u0e23\u0e38\u0e07\u0e04\u0e27\u0e32\u0e21\u0e04\u0e07\u0e2d\u0e22\u0e39\u0e48\u0e41\u0e25\u0e30\u0e1b\u0e23\u0e30\u0e2a\u0e34\u0e17\u0e18\u0e34\u0e1c\u0e25\u0e01\u0e32\u0e23\u0e23\u0e31\u0e01\u0e29\u0e32\u0e02\u0e2d\u0e07\u0e01\u0e32\u0e23\u0e23\u0e31\u0e01\u0e29\u0e32 CAR T-cell \u0e2a\u0e33\u0e2b\u0e23\u0e31\u0e1a\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07 B-cell \u0e40\u0e23\u0e32\u0e15\u0e31\u0e49\u0e07\u0e15\u0e32\u0e23\u0e2d\u0e17\u0e35\u0e48\u0e08\u0e30\u0e1e\u0e31\u0e12\u0e19\u0e32\u0e01\u0e32\u0e23\u0e28\u0e36\u0e01\u0e29\u0e32\u0e02\u0e2d\u0e07\u0e40\u0e23\u0e32\u0e1c\u0e48\u0e32\u0e19\u0e01\u0e32\u0e23\u0e15\u0e23\u0e27\u0e08\u0e2a\u0e2d\u0e1a\u0e43\u0e19\u0e23\u0e48\u0e32\u0e07\u0e01\u0e32\u0e22 \u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e1b\u0e0f\u0e34\u0e27\u0e31\u0e15\u0e34\u0e41\u0e19\u0e27\u0e01\u0e32\u0e23\u0e23\u0e31\u0e01\u0e29\u0e32\u0e2a\u0e33\u0e2b\u0e23\u0e31\u0e1a\u0e1c\u0e39\u0e49\u0e1b\u0e48\u0e27\u0e22\u0e40\u0e2b\u0e25\u0e48\u0e32\u0e19\u0e35\u0e49\u201d<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d777e2d elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no\" data-id=\"d777e2d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-fbc0aee\" data-id=\"fbc0aee\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f42f7db elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"f42f7db\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.16.0 - 14-09-2023 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-default\">\u0e40\u0e07\u0e34\u0e19\u0e17\u0e38\u0e19<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a3809f5 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"a3809f5\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.16.0 - 14-09-2023 *\/\n.elementor-widget-divider{--divider-border-style:none;--divider-border-width:1px;--divider-color:#0c0d0e;--divider-icon-size:20px;--divider-element-spacing:10px;--divider-pattern-height:24px;--divider-pattern-size:20px;--divider-pattern-url:none;--divider-pattern-repeat:repeat-x}.elementor-widget-divider .elementor-divider{display:flex}.elementor-widget-divider .elementor-divider__text{font-size:15px;line-height:1;max-width:95%}.elementor-widget-divider .elementor-divider__element{margin:0 var(--divider-element-spacing);flex-shrink:0}.elementor-widget-divider .elementor-icon{font-size:var(--divider-icon-size)}.elementor-widget-divider .elementor-divider-separator{display:flex;margin:0;direction:ltr}.elementor-widget-divider--view-line_icon .elementor-divider-separator,.elementor-widget-divider--view-line_text .elementor-divider-separator{align-items:center}.elementor-widget-divider--view-line_icon .elementor-divider-separator:after,.elementor-widget-divider--view-line_icon .elementor-divider-separator:before,.elementor-widget-divider--view-line_text .elementor-divider-separator:after,.elementor-widget-divider--view-line_text .elementor-divider-separator:before{display:block;content:\"\";border-bottom:0;flex-grow:1;border-top:var(--divider-border-width) var(--divider-border-style) var(--divider-color)}.elementor-widget-divider--element-align-left .elementor-divider .elementor-divider-separator>.elementor-divider__svg:first-of-type{flex-grow:0;flex-shrink:100}.elementor-widget-divider--element-align-left .elementor-divider-separator:before{content:none}.elementor-widget-divider--element-align-left .elementor-divider__element{margin-left:0}.elementor-widget-divider--element-align-right .elementor-divider .elementor-divider-separator>.elementor-divider__svg:last-of-type{flex-grow:0;flex-shrink:100}.elementor-widget-divider--element-align-right .elementor-divider-separator:after{content:none}.elementor-widget-divider--element-align-right .elementor-divider__element{margin-right:0}.elementor-widget-divider:not(.elementor-widget-divider--view-line_text):not(.elementor-widget-divider--view-line_icon) .elementor-divider-separator{border-top:var(--divider-border-width) var(--divider-border-style) var(--divider-color)}.elementor-widget-divider--separator-type-pattern{--divider-border-style:none}.elementor-widget-divider--separator-type-pattern.elementor-widget-divider--view-line .elementor-divider-separator,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:after,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:before,.elementor-widget-divider--separator-type-pattern:not([class*=elementor-widget-divider--view]) .elementor-divider-separator{width:100%;min-height:var(--divider-pattern-height);-webkit-mask-size:var(--divider-pattern-size) 100%;mask-size:var(--divider-pattern-size) 100%;-webkit-mask-repeat:var(--divider-pattern-repeat);mask-repeat:var(--divider-pattern-repeat);background-color:var(--divider-color);-webkit-mask-image:var(--divider-pattern-url);mask-image:var(--divider-pattern-url)}.elementor-widget-divider--no-spacing{--divider-pattern-size:auto}.elementor-widget-divider--bg-round{--divider-pattern-repeat:round}.rtl .elementor-widget-divider .elementor-divider__text{direction:rtl}.e-con-inner>.elementor-widget-divider,.e-con>.elementor-widget-divider{width:var(--container-widget-width,100%);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e1c8b36 elementor-widget elementor-widget-text-editor\" data-id=\"e1c8b36\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>\u0e07\u0e32\u0e19\u0e19\u0e35\u0e49\u0e44\u0e14\u0e49\u0e23\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e2a\u0e19\u0e31\u0e1a\u0e2a\u0e19\u0e38\u0e19\u0e17\u0e32\u0e07\u0e01\u0e32\u0e23\u0e40\u0e07\u0e34\u0e19\u0e08\u0e32\u0e01\u0e2a\u0e33\u0e19\u0e31\u0e01\u0e07\u0e32\u0e19\u0e1e\u0e31\u0e12\u0e19\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e41\u0e25\u0e30\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34 (\u0e2a\u0e27\u0e17\u0e0a.) (\u0e17\u0e38\u0e19\u0e40\u0e25\u0e02\u0e17\u0e35\u0e48 P-16-50727) \u0e40\u0e04\u0e23\u0e37\u0e2d\u0e02\u0e48\u0e32\u0e22\u0e27\u0e34\u0e08\u0e31\u0e22\u0e19\u0e32\u0e19\u0e32\u0e0a\u0e32\u0e15\u0e34 (IRN) \u0e41\u0e25\u0e30\u0e2a\u0e33\u0e19\u0e31\u0e01\u0e07\u0e32\u0e19\u0e01\u0e2d\u0e07\u0e17\u0e38\u0e19\u0e2a\u0e19\u0e31\u0e1a\u0e2a\u0e19\u0e38\u0e19\u0e01\u0e32\u0e23\u0e27\u0e34\u0e08\u0e31\u0e22 (\u0e2a\u0e01\u0e27.) (\u0e17\u0e38\u0e19\u0e40\u0e25\u0e02\u0e17\u0e35\u0e48 IRN58W0001) \u0e17\u0e38\u0e19\u0e27\u0e34\u0e08\u0e31\u0e22\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e02\u0e2d\u0e07\u0e04\u0e13\u0e30\u0e41\u0e1e\u0e17\u0e22\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e1e\u0e22\u0e32\u0e1a\u0e32\u0e25 (\u0e17\u0e38\u0e19\u0e40\u0e25\u0e02\u0e17\u0e35\u0e48 R016034008) \u0e41\u0e25\u0e30\u0e17\u0e38\u0e19\u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25 (\u0e17\u0e38\u0e19\u0e40\u0e25\u0e02\u0e17\u0e35\u0e48 R016110006 \u0e41\u0e25\u0e30 R016210017) YW \u0e44\u0e14\u0e49\u0e23\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e2a\u0e19\u0e31\u0e1a\u0e2a\u0e19\u0e38\u0e19\u0e08\u0e32\u0e01 International Research Network (IRN)-Ph.D. \u0e17\u0e38\u0e19\u0e01\u0e32\u0e23\u0e28\u0e36\u0e01\u0e29\u0e32 (IRN5801PHDW01). JS \u0e44\u0e14\u0e49\u0e23\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e2a\u0e19\u0e31\u0e1a\u0e2a\u0e19\u0e38\u0e19\u0e08\u0e32\u0e01\u0e17\u0e38\u0e19\u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e21\u0e2b\u0e34\u0e14\u0e25\u0e41\u0e25\u0e30\u0e2a\u0e33\u0e19\u0e31\u0e01\u0e07\u0e32\u0e19\u0e04\u0e13\u0e30\u0e01\u0e23\u0e23\u0e21\u0e01\u0e32\u0e23\u0e19\u0e42\u0e22\u0e1a\u0e32\u0e22\u0e27\u0e34\u0e17\u0e22\u0e32\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c\u0e27\u0e34\u0e08\u0e31\u0e22\u0e41\u0e25\u0e30\u0e19\u0e27\u0e31\u0e15\u0e01\u0e23\u0e23\u0e21\u0e23\u0e30\u0e14\u0e31\u0e1a\u0e2d\u0e38\u0e14\u0e21\u0e28\u0e36\u0e01\u0e29\u0e32\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34 (\u0e2a\u0e27\u0e17\u0e19.) \u0e42\u0e14\u0e22 Program Management Unit-Competitiveness (PMU-C) (\u0e17\u0e38\u0e19\u0e40\u0e25\u0e02\u0e17\u0e35\u0e48 C10F630063) MJ \u0e41\u0e25\u0e30 PYe \u0e44\u0e14\u0e49\u0e23\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e2a\u0e19\u0e31\u0e1a\u0e2a\u0e19\u0e38\u0e19\u0e08\u0e32\u0e01\u0e17\u0e38\u0e19\u0e28\u0e34\u0e23\u0e34\u0e23\u0e32\u0e0a\u0e40\u0e09\u0e25\u0e34\u0e21\u0e1e\u0e23\u0e30\u0e40\u0e01\u0e35\u0e22\u0e23\u0e15\u0e34 MY \u0e44\u0e14\u0e49\u0e23\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e2a\u0e19\u0e31\u0e1a\u0e2a\u0e19\u0e38\u0e19\u0e08\u0e32\u0e01 \u0e2a\u0e27\u0e17\u0e19. (\u0e27\u0e17.) (\u0e40\u0e25\u0e02\u0e17\u0e35\u0e48 RTA6180012) \u0e41\u0e25\u0e30\u0e2a\u0e33\u0e19\u0e31\u0e01\u0e07\u0e32\u0e19\u0e04\u0e13\u0e30\u0e01\u0e23\u0e23\u0e21\u0e01\u0e32\u0e23\u0e27\u0e34\u0e08\u0e31\u0e22\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34 (\u0e40\u0e25\u0e02\u0e17\u0e35\u0e48 \u0e27\u0e0a.808\/2563)<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a3c7bb6 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no\" data-id=\"a3c7bb6\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e51aa36\" data-id=\"e51aa36\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-61b459f elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"61b459f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\n\u0e01\u0e23\u0e30\u0e14\u0e32\u0e29\u0e15\u0e49\u0e19\u0e09\u0e1a\u0e31\u0e1a<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e2c38ec elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"e2c38ec\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f7592ce elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"f7592ce\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>\u0e0a\u0e37\u0e48\u0e2d\u0e1a\u0e17\u0e04\u0e27\u0e32\u0e21\u0e15\u0e49\u0e19\u0e09\u0e1a\u0e31\u0e1a:<\/strong> \u0e01\u0e32\u0e23\u0e1e\u0e31\u0e12\u0e19\u0e32 CAR Anti-CD19 \u0e41\u0e1a\u0e1a\u0e43\u0e2b\u0e21\u0e48\u0e17\u0e35\u0e48\u0e21\u0e35 scFv \u0e02\u0e2d\u0e07\u0e21\u0e19\u0e38\u0e29\u0e22\u0e4c\u0e2d\u0e22\u0e48\u0e32\u0e07\u0e2a\u0e21\u0e1a\u0e39\u0e23\u0e13\u0e4c\u0e41\u0e25\u0e30\u0e42\u0e14\u0e40\u0e21\u0e19\u0e17\u0e35\u0e48\u0e04\u0e33\u0e19\u0e27\u0e13\u0e15\u0e49\u0e19\u0e17\u0e38\u0e19\u0e44\u0e14\u0e49\u0e2a\u0e32\u0e21\u0e42\u0e14\u0e40\u0e21\u0e19<br \/><strong>\u0e27\u0e32\u0e23\u0e2a\u0e32\u0e23: <\/strong>\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e27\u0e34\u0e17\u0e22\u0e32\u0e0a\u0e32\u0e22\u0e41\u0e14\u0e19<span class=\"anchor-text\"><br \/><\/span><strong>\u0e14\u0e2d\u0e22: <\/strong><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fonc.2021.802876\/full\">10.3389\/fonc.2021.802876<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d96249a elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no\" data-id=\"d96249a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3f13380\" data-id=\"3f13380\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-490a2b5 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"490a2b5\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u0e08\u0e14\u0e2b\u0e21\u0e32\u0e22\u0e42\u0e15\u0e49\u0e15\u0e2d\u0e1a<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c252356 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"c252356\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2556c35 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"2556c35\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span class=\"text surname\"><a href=\"https:\/\/sites.google.com\/view\/sicore-cit\/about-us\/staff\/a_pa-thai-yenchitsomanus\"><span class=\"given-name\">\u0e1c\u0e31\u0e14\u0e44\u0e17<\/span>\u00a0<\/a><a href=\"https:\/\/sites.google.com\/view\/sicore-cit\/about-us\/staff\/a_pa-thai-yenchitsomanus\">\u0e40\u0e22\u0e47\u0e19\u0e08\u0e34\u0e15\u0e42\u0e2a\u0e21\u0e19\u0e31\u0e2a<\/a><\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2101dec elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no\" data-id=\"2101dec\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-dada8b3\" data-id=\"dada8b3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-064bddf elementor-widget__width-initial elementor-widget elementor-widget-jkit_social_share\" data-id=\"064bddf\" data-element_type=\"widget\" data-widget_type=\"jkit_social_share.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div  class=\"jeg-elementor-kit jkit-social-share jeg_module___6abf1de0b5dff\" ><ul class=\"social-share-list\"><li class=\"elementor-repeater-item-14d1b21\" data-social=\"facebook\">\n\t\t\t\t<a class=\"facebook social-icon\"><span class=\"icon-position-before\"><i aria-hidden=\"true\" class=\"fab fa-facebook-f\"><\/i>\u0e40\u0e1f\u0e2a\u0e1a\u0e38\u0e4a\u0e04<\/span><\/a>\n\t\t\t<\/li><li class=\"elementor-repeater-item-ee9a855\" data-social=\"twitter\">\n\t\t\t\t<a class=\"twitter social-icon\"><span class=\"icon-position-before\"><i aria-hidden=\"true\" class=\"fab fa-twitter\"><\/i>\u0e17\u0e27\u0e34\u0e15\u0e40\u0e15\u0e2d\u0e23\u0e4c<\/span><\/a>\n\t\t\t<\/li><li class=\"elementor-repeater-item-4a6d796\" data-social=\"line\">\n\t\t\t\t<a class=\"line social-icon\"><span class=\"icon-position-before\"><i aria-hidden=\"true\" class=\"fab fa-line\"><\/i>\u0e40\u0e2a\u0e49\u0e19<\/span><\/a>\n\t\t\t<\/li><\/ul><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Photo by RF._.studio\/pexels\u00a0 In a significant advancement for the treatment of B-cell malignancies, researchers have developed a new generation of chimeric antigen receptor (CAR) T cells with fully human-derived components, offering potential improvements over current therapies. CAR T-cell therapy has shown effectiveness in treating B-cell malignancies, but the persistence of certain CAR T cells and&#8230;<\/p>","protected":false},"author":2,"featured_media":14470,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[105],"tags":[102],"class_list":["post-14468","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-news-research-news","tag-tag-news-mu"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.2 - aioseo.com -->\n\t<meta name=\"description\" content=\"In a significant advancement for the treatment of B-cell malignancies, researchers have developed a new generation of chimeric antigen receptor (CAR) T cells with fully human-derived components,\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"admin\"\/>\n\t<link rel=\"canonical\" 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