Researchers from Chulalongkorn University have successfully established a novel human antibody heavy chain variable (VH)-only domain with potent activity against folate receptor alpha-positive solid tumor in CAR-T cell format....
Researchers from Chulalongkorn University have successfully developed MUC1-targeting CAR T cells engineered to secrete an anti-PD-1 antibody, derived from nivolumab, to enhance their effectiveness against solid tumors. These modified...
Researchers from Chulalongkorn University have developed a new weapon against glioblastoma, a notoriously difficult-to-treat brain cancer, in the form of a brand-new antibody. This antibody is a key component...
Researchers from Chulalongkorn University have developed a new weapon against glioblastoma, a notoriously difficult-to-treat brain cancer, in the form of a brand-new antibody. This antibody is a key component...
This study compared different CAR T cell designs and found that using a CD8α spacer and tumor necrosis factor receptor (TNFR)-based costimulation (4-1BB or CD27) enhanced the treatment’s efficacy....
Exciting Breakthrough in CAR-T Cell Therapy Offers New Hope for Solid Tumor Treatment. In a groundbreaking study that could revolutionize cancer treatment, researchers have unveiled a new CAR-T cell...
In an exciting development in the field of cancer immunotherapy, researchers have engineered a new dual-target CAR T-cell therapy that simultaneously targets two key antigens, CD19 and CD20, in...
Image by Erin_Hinterland/pixabay A groundbreaking study has delved into the potential interactions between cannabidiol (CBD) and CD19-chimeric antigen receptor (CAR) T cell therapy, a promising approach in cancer immunotherapy....
Image by Herney/pixabay In a notable advancement in cell engineering research, scientists have developed the first ligand-based, piggyBac-transfected anti-EGFR CAR-T cells, targeting non-small cell lung cancer (NSCLC). NSCLC often...
The researchers from Chulalongkorn University developed an effective way to grow cytokine-induced killer (CIK) cells using a gas-permeable culture method. This method allowed them to produce a large number...