BackPreclinical evaluation of a novel CAR-T therapy utilizing a scFv antibody highly specific to MAGE-A4p230-239/HLA-A∗02:01 complexJune 5, 2024Read MoreArtificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian CancerMay 31, 2024Read MoreResearch Highlights and TTCI Internal Meeting Part IIMay 30, 2024Read MoreResearch Highlights and TTCI Internal Meeting Part IMay 27, 2024Read MoreSynthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapiesMay 1, 2024Read MoreNon-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemiaApril 3, 2024Read MoreSynthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor responseFebruary 28, 2024Read MoreIL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastasesFebruary 28, 2024Read MoreAllogeneic gene-edited HIV-specific CAR-T cells secreting PD-1 blocking scFv enhance specific cytotoxic activity against HIV Env+ cells in vivoJanuary 24, 2024Read MoreDeletion of the inhibitory co-receptor CTLA-4 enhances and invigorates chimeric antigen receptor T cellsNovember 29, 2023Read MoreTargeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapyOctober 25, 2023Read MoreDeletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapySeptember 27, 2023Read MoreOlder PostsNewer Posts
Preclinical evaluation of a novel CAR-T therapy utilizing a scFv antibody highly specific to MAGE-A4p230-239/HLA-A∗02:01 complexJune 5, 2024Read More
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian CancerMay 31, 2024Read More
Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapiesMay 1, 2024Read More
Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemiaApril 3, 2024Read More
Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor responseFebruary 28, 2024Read More
IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastasesFebruary 28, 2024Read More
Allogeneic gene-edited HIV-specific CAR-T cells secreting PD-1 blocking scFv enhance specific cytotoxic activity against HIV Env+ cells in vivoJanuary 24, 2024Read More
Deletion of the inhibitory co-receptor CTLA-4 enhances and invigorates chimeric antigen receptor T cellsNovember 29, 2023Read More
Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapyOctober 25, 2023Read More
Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapySeptember 27, 2023Read More