Image by Herney/pixabay In a notable advancement in cell engineering research, scientists have developed the first ligand-based, piggyBac-transfected anti-EGFR CAR-T cells, targeting non-small cell lung cancer (NSCLC). NSCLC often...
Image by Belova59/pixabay The reversibility of butyrophilin-like1 (Btnl1)-deficience in mice suggested cancer cells thrive in the absence of Vγ7+ cells, which play the pivotal role of human and mouse...
Image by fernandozhiminaicela/pixabay Nucleolin (NCL) has a functional role in cancer regulation. Targeting surface NCL impaired the progression of several cancer cell types in vitro and in vivo. The...
Image by AhmadArdity/pixabay Carcinoma-associated fibroblasts (CAFs) secrete IL-6-induced doxorubicin (Dox) resistance and PD-L1 expression through STAT3 and AKT pathways, play a critical role in breast cancer progression and reduce...
Image by bdyczewski/pixabay S100 calcium-binding protein A2 (S100A2) which has been proposed as a potential marker in many types of cancer, however, the prognostic value of S100A2 in colorectal...
Photo by Karolina Grabowska/pexels Cholangiocarcinoma (CCA), a highly aggressive and deadly cancer, poses significant challenges in terms of effective treatment options and patient survival rates. In the quest for...
Recent advancements in cholangiocarcinoma (CCA) research have been marked by the innovative use of three-dimensional multicellular spheroid (3D MCS) models. These models, which replicate the 3D architecture and multicellular...
Image by Chokniti Khongchum/pexels A team of researchers from Faculty of Medicine Siriraj Hospital, Mahidol University, has made a significant stride in the fight against cholangiocarcinoma (CCA), a highly...
The researchers from Chulalongkorn University developed an effective way to grow cytokine-induced killer (CIK) cells using a gas-permeable culture method. This method allowed them to produce a large number...
Photo by Kitt_KS Cholangiocarcinoma (CCA), a type of liver cancer, is driven by oxidative stress and chronic inflammation. Researchers from Khon Kaen University have made a significant breakthrough by...