Researchers have found a new way to make the body’s immune cells (T cells) fight lung cancer more effectively. They used a special “connector” protein that helps T cells recognize and kill cancer cells that have a specific marker called PD-L1. When this connector protein was combined with a common chemotherapy drug called gemcitabine, it made the T cells even better at destroying the cancer. This new combination treatment looks promising for improving how we treat lung cancer.
เงินทุน
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กระดาษต้นฉบับ
ชื่อบทความต้นฉบับ: Enhancing T cell cytotoxicity against lung cancer with an αPD-L1 protein engager and gemcitabine combination therapy.
วารสาร: Biomedicine & Pharmacotherapy (Biomed Pharmacother)
ดอย: 10.1016/j.biopha.2025.118161
จดหมายโต้ตอบ
อัสสราปัญญา
Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand; Cell Engineering for Cancer Therapy Research Group, Chiang Mai University, Chiang Mai 50200, Thailand.
อีเมล: [email protected]